It’s only a problem if you actually want those files included in the backup.
If so, then check your --snapshot-policy - you may need to enable it so in-use files can be included in backups.
`–snapshot-policy=Auto|On|Off|Required
This setting controls the usage of snapshots, which allows Duplicati to backup files that are locked by other programs. If this is set to “off”, Duplicati will not attempt to create a disk snapshot. Setting this to “auto” makes Duplicati attempt to create a snapshot, and fail silently if that was not allowed or supported (note that the OS may still log system warnings). A setting of “on” will also make Duplicati attempt to create a snapshot, but will produce a warning message in the log if it fails. Setting it to “required” will make Duplicati abort the backup if the snapshot creation fails. On windows this uses the Volume Shadow Copy Services (VSS) and requires administrative privileges. On Linux this uses Logical Volume Management (LVM) and requires root privileges.
Default value: “off”