Hi @atti_effe, welcome to the forum 
This seems to be caused by the power-savings mode not working correctly.
What happens is that Duplicati will pause itself when the machine is in low-power mode.
When leaving low-power mode, Duplicati is supposed to resume itself, but in some cases it does not. It is hard to track, but so far the guess is that something in .NET “forgets” to forward the event, so Duplicati never notices the transition.
On the settings page, you should see a section title “Power mode provider”. You can try the “Native” one if you prefer the feature in general, or “None” to disable the auto-pause feature.