Thanks for your reply!
The whole backup has 900 GB, not the database - sorry 
I’ve tried to repair the database and this is the error out of the debug log:
Sep 14, 2019 11:57 AM: The operation Repair has failed with error: The backup storage destination is missing data files. You can either enable --rebuild-missing-dblock-files
or run the purge command to remove these files. The following files are missing: duplicati-b3722facd53ae42cb98f438d137af4df1.dblock.zip.aes
{“ClassName”:“Duplicati.Library.Interface.UserInformationException”,“Message”:“The backup storage destination is missing data files. You can either enable --rebuild-missing-dblock-files
or run the purge command to remove these files. The following files are missing: duplicati-b3722facd53ae42cb98f438d137af4df1.dblock.zip.aes”,“Data”:null,“InnerException”:null,“HelpURL”:null,“StackTraceString”:" bei Duplicati.Library.Main.Operation.RepairHandler.RunRepairRemote()\r\n bei Duplicati.Library.Main.Operation.RepairHandler.Run(IFilter filter)\r\n bei Duplicati.Library.Main.Controller.RunAction[T](T result, String& paths, IFilter& filter, Action`1 method)\r\n bei Duplicati.Library.Main.Controller.Repair(IFilter filter)\r\n bei Duplicati.Server.Runner.Run(IRunnerData data, Boolean fromQueue)",“RemoteStackTraceString”:null,“RemoteStackIndex”:0,“ExceptionMethod”:“8\nRunRepairRemote\nDuplicati.Library.Main, Version=2.0.4.23, Culture=neutral, PublicKeyToken=null\nDuplicati.Library.Main.Operation.RepairHandler\nVoid RunRepairRemote()”,“HResult”:-2146233088,“Source”:“Duplicati.Library.Main”,“WatsonBuckets”:null}
Now I’ll try to purge this file…
Finished!
Listing remote folder …
Uploading file (18,80 MB) …
Deleting file duplicati-20190609T143937Z.dlist.zip.aes …
Return code: 0
Okay, why did it work today… Now I’ll try to do a full backup again.
Edit2:
Oh no… Now the network path cannot be found:
Sep 14, 2019 12:45 PM: Failed while executing “Backup” with id: 2
System.IO.IOException: Der Netzwerkpfad wurde nicht gefunden.
bei System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
bei System.IO.DriveInfo.get_TotalSize()
bei Duplicati.Library.Backend.File.get_Quota()
bei Duplicati.Library.Main.Operation.FilelistProcessor.RemoteListAnalysis(BackendManager backend, Options options, LocalDatabase database, IBackendWriter log, String protectedfile)
bei Duplicati.Library.Main.Operation.FilelistProcessor.VerifyRemoteList(BackendManager backend, Options options, LocalDatabase database, IBackendWriter log, String protectedfile)
bei Duplicati.Library.Main.Operation.BackupHandler.PreBackupVerify(BackendManager backend, String protectedfile)
bei Duplicati.Library.Main.Operation.BackupHandler.d__19.MoveNext()
— Ende der Stapelüberwachung vom vorhergehenden Ort, an dem die Ausnahme ausgelöst wurde —
bei System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()
bei CoCoL.ChannelExtensions.WaitForTaskOrThrow(Task task)
bei Duplicati.Library.Main.Controller.<>c__DisplayClass13_0.b__0(BackupResults result)
bei Duplicati.Library.Main.Controller.RunAction[T](T result, String& paths, IFilter& filter, Action`1 method)
bei Duplicati.Library.Main.Controller.Backup(String inputsources, IFilter filter)
bei Duplicati.Server.Runner.Run(IRunnerData data, Boolean fromQueue)
What now?
Edit3
Now it’s working… But I forgot to exclude one folder.
So I stopped the backup, added the exclusion.
But now I’ve got an even bigger problem when I’m trying to start the backup again:
Sep 14, 2019 2:31 PM: The operation Backup has failed with error: Detected non-empty blocksets with no associated blocks!
{“ClassName”:“System.Exception”,“Message”:“Detected non-empty blocksets with no associated blocks!”,“Data”:null,“InnerException”:null,“HelpURL”:null,“StackTraceString”:" bei Duplicati.Library.Main.Database.LocalDatabase.VerifyConsistency(Int64 blocksize, Int64 hashsize, Boolean verifyfilelists, IDbTransaction transaction)\r\n bei Duplicati.Library.Main.Operation.Backup.BackupDatabase.<>c__DisplayClass32_0.b__0()\r\n bei Duplicati.Library.Main.Operation.Common.SingleRunner.<>c__DisplayClass3_0.b__0()\r\n bei Duplicati.Library.Main.Operation.Common.SingleRunner.d__21.MoveNext()\r\n--- Ende der Stapelüberwachung vom vorhergehenden Ort, an dem die Ausnahme ausgelöst wurde ---\r\n bei System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()\r\n bei System.Runtime.CompilerServices.TaskAwaiter.HandleNonSuccessAndDebuggerNotification(Task task)\r\n bei Duplicati.Library.Main.Operation.BackupHandler.<RunAsync>d__19.MoveNext()\r\n--- Ende der Stapelüberwachung vom vorhergehenden Ort, an dem die Ausnahme ausgelöst wurde ---\r\n bei System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()\r\n bei CoCoL.ChannelExtensions.WaitForTaskOrThrow(Task task)\r\n bei Duplicati.Library.Main.Controller.<>c__DisplayClass13_0.<Backup>b__0(BackupResults result)\r\n bei Duplicati.Library.Main.Controller.RunAction[T](T result, String[]& paths, IFilter& filter, Action
1 method)\r\n bei Duplicati.Library.Main.Controller.Backup(String inputsources, IFilter filter)\r\n bei Duplicati.Server.Runner.Run(IRunnerData data, Boolean fromQueue)",“RemoteStackTraceString”:null,“RemoteStackIndex”:0,“ExceptionMethod”:“8\nVerifyConsistency\nDuplicati.Library.Main, Version=2.0.4.23, Culture=neutral, PublicKeyToken=null\nDuplicati.Library.Main.Database.LocalDatabase\nVoid VerifyConsistency(Int64, Int64, Boolean, System.Data.IDbTransaction)”,“HResult”:-2146233088,“Source”:“Duplicati.Library.Main”,“WatsonBuckets”:null}
Repair does not help either… HELP PLEASE!