Yeah, that was a problem first but I migrated Duplicati to run as a service based on this: Migrating from User to Service install on Windows - How-To - Duplicati
However, it was suspicous that after a reboot not all of my jobs was showing up in the GUI, I had to stop the application and restart the service. I assume this migration was not succesful completely. Duplicati service is running as a local system account now. Duplicati as an application is not running now (no system tray icon) and I access the GUI on localhost:8200