The “incompatibility with 64-bit version of Windows” has only come up once before here that I can find.
Duplicati as a service in Windows 10 fixed it with an uninstall and reinstall of Duplicati. You could try…
Do any of the Duplicati .exe files run, e.g. does Duplicati.CommandLine.exe help do help screen?
Your Duplicati version needs .NET Framework 4.6.2 or higher.