Hi!
I am running 2.1.0.4 version on Debian 12 and it works well. Duplicati does not give any errors or warnings, but in the server logs I find a lot of these:
Feb 06 03:00:00 KnoxIII duplicati-server[904241]: SQLite warning (284): automatic index on B(BlocksetID)
…
Feb 06 03:03:06 KnoxIII duplicati-server[904241]: SQLite warning (284): automatic index on B(VolumeID)
This particular backup starts at 3.00 and took 4:23 minutes, so the first warning is just at start, and the last i a bit before the end.