Choosing sizes in Duplicati gives some background if you pursue that route. The size that can prevent you from having more than 5000 is the –dblock-size which defaults to 50 MB. What I personally would consider the chunk size is –blocksize and defaults to 100 KB, which OneDrive won’t see, but Duplicati will, so there gets to be a huge amount of block tracking, and things such as database operations can become very slow. There are no hard-and-fast rules, and not really much systematic testing, but some like to use --blocksize of 1 MB for large backups. --dblock-size is the “Remote volume size” of screen 5 Options. Despite its warning, people sometimes think it’s the entire size of remote storage, so set it to higher values than you would while simply trying to upload your blocks in larger dblock bundles. You’ll probably hit a OneDrive limit first. I see some web citations that they have a 15 GB limit on the file size. Zip-compression-zip64 clarification suggests that Duplicati’s dblock size limit is roughly 16 EiB per this.
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