Yes. That’s currently a manual step with Duplicati.WindowsService.exe and a Microsoft pitfall where the SYSTEM profile that Duplicati is in by default gets moved into Windows.old during their version upgrade.
Installing Duplicati on Windows shows a new service install.
Duplicati Tutorial 02 Install Duplicati as a Service is a video.
Migrating from User to Service install on Windows is a forum topic that gets into configuration migrations.