Duplicati Error when testing connection to S3 Compatible storage

I have a strange occurrence that I have been unable to resolve
We have two office locations each with a server running Duplicati, plus i have a TrueNAS Core server at home to back up both locations using MinIO
First location I set up works great, 2nd location gives this error when testing connection to MinIO in Duplicati:
“Failed to connect: MinIO API responded with message=unsuccessful response from server without XML error. The request was aborted. Could not create SSL/TLS secure channel.”
Both server are using the same Access ID and same Access Key, but pointing to different buckets.
Really hoping someone out there has an inspirational idea that resolves this, since I am completely baffled why one works and the other doesn’t.
Thanking you in advance.

Doing some online research and found mention of .NET compatibility issues. Updating .NET on the server that is not working and will post results here once know.