Is Duplicati 2 ready for production? has other anecdotal comments and some statistics. I think it does vary. Generally it’s best practice to create multiple backups using different software, especially if files are critical.
Duplicati is young software and still in beta because problems do occur from time to time. Study the forum. The tech talk Duplicati provides helps with assisted diagnosis now, and may lead to better messages later.
My personal opinion is that Duplicati is better suited for shorter-term protection than historical file recovery. What worries me greatly is people who put their files in Duplicati then delete original files to make space…
My personal use is I trust it enough to use it, but not in ways that would hurt a lot, if something goes wrong. Addditionally, I do test restores from time to time (they work), which I recommend for any backup software.
Good luck in your search!